Intercepting the Atopic March: Can Early Management Change the Trajectory?

The atopic march refers to the progressive development of atopic disorders, beginning with atopic dermatitis in infancy, followed by food allergies, allergic rhinitis, and asthma. Early immune dysregulation and skin barrier dysfunction are key drivers. Intercepting this progression through early interventions, such as optimal skin care (emollient therapy), allergen avoidance, and early introduction of certain foods, may alter immune responses and reduce sensitisation. Emerging evidence suggests that timely management of atopic dermatitis and targeted immunomodulatory therapies may delay or prevent the onset of subsequent atopic conditions. Understanding genetic and environmental factors is critical to developing personalised prevention strategies and altering the disease trajectory.

Dr. Shelly Radhakrishnan

MBBS, MD - Paediatrics, Consultant Paediatrician & Private Practitioner at JS Hospital, Karaikudi, and Dr. Shelly's Child Clinic

Speaker